kn 62 Search Results


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Tocris cas 57265 65 3 kn 62 tocris
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Selleck Chemicals p2x7r inhibitor kn62
Fig. 5. Nitrated Hsp90 proliferative activity is mediated by activation of <t>P2X7R.</t> (A) Schwannoma (MN-Schwann cells), and (B) normal Schwann cell growth was assessed in the presence and absence of the P2X7R inhibitor KN-62 (10 μM). (C–D) Recombinant proteins were intracellularly delivered to schwannoma and normal Schwann cells and the cells incubated for 24 and 48 h in the presence and absence of the P2X7R inhibitor <t>KN62</t> (10 μM). The ECAR and glycolytic parameters of (E–G) schwannoma cells, and (H–J) normal Schwann cells were measured 24 h after delivery. Data is shown using Tukey’s representation with the median indicated in the box plot and outliers indicated with dots (n = 3–8 with 8 replicates). *p < 0.05 versus Hsp90 by one-way ANOVA with Dunnett’s multiple com parisons post hoc test.
P2x7r Inhibitor Kn62, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Santa Cruz Biotechnology kn 62
Fig. 5. Nitrated Hsp90 proliferative activity is mediated by activation of <t>P2X7R.</t> (A) Schwannoma (MN-Schwann cells), and (B) normal Schwann cell growth was assessed in the presence and absence of the P2X7R inhibitor KN-62 (10 μM). (C–D) Recombinant proteins were intracellularly delivered to schwannoma and normal Schwann cells and the cells incubated for 24 and 48 h in the presence and absence of the P2X7R inhibitor <t>KN62</t> (10 μM). The ECAR and glycolytic parameters of (E–G) schwannoma cells, and (H–J) normal Schwann cells were measured 24 h after delivery. Data is shown using Tukey’s representation with the median indicated in the box plot and outliers indicated with dots (n = 3–8 with 8 replicates). *p < 0.05 versus Hsp90 by one-way ANOVA with Dunnett’s multiple com parisons post hoc test.
Kn 62, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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LC Laboratories camkii reagents kn-62
Fig. 5. Nitrated Hsp90 proliferative activity is mediated by activation of <t>P2X7R.</t> (A) Schwannoma (MN-Schwann cells), and (B) normal Schwann cell growth was assessed in the presence and absence of the P2X7R inhibitor KN-62 (10 μM). (C–D) Recombinant proteins were intracellularly delivered to schwannoma and normal Schwann cells and the cells incubated for 24 and 48 h in the presence and absence of the P2X7R inhibitor <t>KN62</t> (10 μM). The ECAR and glycolytic parameters of (E–G) schwannoma cells, and (H–J) normal Schwann cells were measured 24 h after delivery. Data is shown using Tukey’s representation with the median indicated in the box plot and outliers indicated with dots (n = 3–8 with 8 replicates). *p < 0.05 versus Hsp90 by one-way ANOVA with Dunnett’s multiple com parisons post hoc test.
Camkii Reagents Kn 62, supplied by LC Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Biomol GmbH kn-62 (biomol)
Fig. 5. Nitrated Hsp90 proliferative activity is mediated by activation of <t>P2X7R.</t> (A) Schwannoma (MN-Schwann cells), and (B) normal Schwann cell growth was assessed in the presence and absence of the P2X7R inhibitor KN-62 (10 μM). (C–D) Recombinant proteins were intracellularly delivered to schwannoma and normal Schwann cells and the cells incubated for 24 and 48 h in the presence and absence of the P2X7R inhibitor <t>KN62</t> (10 μM). The ECAR and glycolytic parameters of (E–G) schwannoma cells, and (H–J) normal Schwann cells were measured 24 h after delivery. Data is shown using Tukey’s representation with the median indicated in the box plot and outliers indicated with dots (n = 3–8 with 8 replicates). *p < 0.05 versus Hsp90 by one-way ANOVA with Dunnett’s multiple com parisons post hoc test.
Kn 62 (Biomol), supplied by Biomol GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Microm International GmbH kn-62
Fig. 5. Nitrated Hsp90 proliferative activity is mediated by activation of <t>P2X7R.</t> (A) Schwannoma (MN-Schwann cells), and (B) normal Schwann cell growth was assessed in the presence and absence of the P2X7R inhibitor KN-62 (10 μM). (C–D) Recombinant proteins were intracellularly delivered to schwannoma and normal Schwann cells and the cells incubated for 24 and 48 h in the presence and absence of the P2X7R inhibitor <t>KN62</t> (10 μM). The ECAR and glycolytic parameters of (E–G) schwannoma cells, and (H–J) normal Schwann cells were measured 24 h after delivery. Data is shown using Tukey’s representation with the median indicated in the box plot and outliers indicated with dots (n = 3–8 with 8 replicates). *p < 0.05 versus Hsp90 by one-way ANOVA with Dunnett’s multiple com parisons post hoc test.
Kn 62, supplied by Microm International GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Seikagaku corporation kn-62
Fig. 5. Nitrated Hsp90 proliferative activity is mediated by activation of <t>P2X7R.</t> (A) Schwannoma (MN-Schwann cells), and (B) normal Schwann cell growth was assessed in the presence and absence of the P2X7R inhibitor KN-62 (10 μM). (C–D) Recombinant proteins were intracellularly delivered to schwannoma and normal Schwann cells and the cells incubated for 24 and 48 h in the presence and absence of the P2X7R inhibitor <t>KN62</t> (10 μM). The ECAR and glycolytic parameters of (E–G) schwannoma cells, and (H–J) normal Schwann cells were measured 24 h after delivery. Data is shown using Tukey’s representation with the median indicated in the box plot and outliers indicated with dots (n = 3–8 with 8 replicates). *p < 0.05 versus Hsp90 by one-way ANOVA with Dunnett’s multiple com parisons post hoc test.
Kn 62, supplied by Seikagaku corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Enzo Biochem kn-62
Fig. 5. Nitrated Hsp90 proliferative activity is mediated by activation of <t>P2X7R.</t> (A) Schwannoma (MN-Schwann cells), and (B) normal Schwann cell growth was assessed in the presence and absence of the P2X7R inhibitor KN-62 (10 μM). (C–D) Recombinant proteins were intracellularly delivered to schwannoma and normal Schwann cells and the cells incubated for 24 and 48 h in the presence and absence of the P2X7R inhibitor <t>KN62</t> (10 μM). The ECAR and glycolytic parameters of (E–G) schwannoma cells, and (H–J) normal Schwann cells were measured 24 h after delivery. Data is shown using Tukey’s representation with the median indicated in the box plot and outliers indicated with dots (n = 3–8 with 8 replicates). *p < 0.05 versus Hsp90 by one-way ANOVA with Dunnett’s multiple com parisons post hoc test.
Kn 62, supplied by Enzo Biochem, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Biaffin Inc kn-62
Fig. 5. Nitrated Hsp90 proliferative activity is mediated by activation of <t>P2X7R.</t> (A) Schwannoma (MN-Schwann cells), and (B) normal Schwann cell growth was assessed in the presence and absence of the P2X7R inhibitor KN-62 (10 μM). (C–D) Recombinant proteins were intracellularly delivered to schwannoma and normal Schwann cells and the cells incubated for 24 and 48 h in the presence and absence of the P2X7R inhibitor <t>KN62</t> (10 μM). The ECAR and glycolytic parameters of (E–G) schwannoma cells, and (H–J) normal Schwann cells were measured 24 h after delivery. Data is shown using Tukey’s representation with the median indicated in the box plot and outliers indicated with dots (n = 3–8 with 8 replicates). *p < 0.05 versus Hsp90 by one-way ANOVA with Dunnett’s multiple com parisons post hoc test.
Kn 62, supplied by Biaffin Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ICN Pharmaceuticals kn-62 inhibitor
Fig. 5. Nitrated Hsp90 proliferative activity is mediated by activation of <t>P2X7R.</t> (A) Schwannoma (MN-Schwann cells), and (B) normal Schwann cell growth was assessed in the presence and absence of the P2X7R inhibitor KN-62 (10 μM). (C–D) Recombinant proteins were intracellularly delivered to schwannoma and normal Schwann cells and the cells incubated for 24 and 48 h in the presence and absence of the P2X7R inhibitor <t>KN62</t> (10 μM). The ECAR and glycolytic parameters of (E–G) schwannoma cells, and (H–J) normal Schwann cells were measured 24 h after delivery. Data is shown using Tukey’s representation with the median indicated in the box plot and outliers indicated with dots (n = 3–8 with 8 replicates). *p < 0.05 versus Hsp90 by one-way ANOVA with Dunnett’s multiple com parisons post hoc test.
Kn 62 Inhibitor, supplied by ICN Pharmaceuticals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Fig. 5. Nitrated Hsp90 proliferative activity is mediated by activation of P2X7R. (A) Schwannoma (MN-Schwann cells), and (B) normal Schwann cell growth was assessed in the presence and absence of the P2X7R inhibitor KN-62 (10 μM). (C–D) Recombinant proteins were intracellularly delivered to schwannoma and normal Schwann cells and the cells incubated for 24 and 48 h in the presence and absence of the P2X7R inhibitor KN62 (10 μM). The ECAR and glycolytic parameters of (E–G) schwannoma cells, and (H–J) normal Schwann cells were measured 24 h after delivery. Data is shown using Tukey’s representation with the median indicated in the box plot and outliers indicated with dots (n = 3–8 with 8 replicates). *p < 0.05 versus Hsp90 by one-way ANOVA with Dunnett’s multiple com parisons post hoc test.

Journal: Redox biology

Article Title: Selective nitration of Hsp90 acts as a metabolic switch promoting tumor cell proliferation.

doi: 10.1016/j.redox.2024.103249

Figure Lengend Snippet: Fig. 5. Nitrated Hsp90 proliferative activity is mediated by activation of P2X7R. (A) Schwannoma (MN-Schwann cells), and (B) normal Schwann cell growth was assessed in the presence and absence of the P2X7R inhibitor KN-62 (10 μM). (C–D) Recombinant proteins were intracellularly delivered to schwannoma and normal Schwann cells and the cells incubated for 24 and 48 h in the presence and absence of the P2X7R inhibitor KN62 (10 μM). The ECAR and glycolytic parameters of (E–G) schwannoma cells, and (H–J) normal Schwann cells were measured 24 h after delivery. Data is shown using Tukey’s representation with the median indicated in the box plot and outliers indicated with dots (n = 3–8 with 8 replicates). *p < 0.05 versus Hsp90 by one-way ANOVA with Dunnett’s multiple com parisons post hoc test.

Article Snippet: The P2X7R inhibitor KN62 (10 μM, Cat. no. S7422, Selleck Chemicals) was dissolved in DMSO and administred at the final concentration indicated.

Techniques: Activity Assay, Activation Assay, Recombinant, Incubation